Tenofovir Disoproxil
Product Description
| Catalogue Number | T018508 |
| Chemical Name | Tenofovir Disoproxil |
| Synonyms | 5-[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]-bis(1-methylethyl)ester-5-oxide-2,4,6,8-tetraoxa-5-phosphanonanedioic Acid; (R)-5-[[2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]-bis(1-methylethyl)ester-5-oxide-2,4,6,8-tetraoxa-5-phosphanonanedioic Acid; Bis-POC-PMPA; GS 4331; |
| CAS Number | 201341-05-1 |
| Molecular Formula | C19H30N5O10P |
| Molecular Weight | 519.44 |
| Category | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | Tenofovir Disoproxil is a therapeutic option for nucleos(t)ide analog (NA)-experienced chronic hepatitis B (CHB) patients infected with hepatitis B virus (HBV). Also, it is an intermediate used in the synthesis of Tenofovir Disoproxil Dimer (T018515), which is a Tenofovir Disoproxil impurity. |
| References | Huang, M., et al.: Clin. Drug Investig., 36, 471-478 (2016); Cheng, G., et al.: Chem. Res. Toxicol., 16, 145 (2003) |
