Tamoxifen Citrate
Product Description
| Catalogue Number | T006090 |
| Chemical Name | Tamoxifen Citrate |
| Synonyms | (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine 2-Hydroxy-1,2,3-propanetricarboxylate; 2-[4-[(1Z)-1,2-Diphenyl-1-butenyl]phenoxy]-N,N-dimethylethanamine 2-Hydroxy-1,2,3-Propanetricarboxylate; I.C.I.46474 citrate; ICI 46474; Istubal; Kessar; Noltam; Nolvadex; Nourytam; Soltamox; TMX; Tamofen; Tamoplex; Tamox-Puren; Tamoxifen Citrate; Tomaxasta; Valodex; Z-Tamoxifen Citrate; Zemide; |
| CAS Number | 54965-24-1 |
| Alternate CAS # | Free Base: 10540-29-1 |
| Molecular Formula | C₂₆H₂₉NO•C₆H₈O₇ |
| Appearance | White Solid |
| Melting Point | >143°C (dec.) |
| Molecular Weight | 563.24 |
| Storage | 4°C |
| Solubility | Chloroform (Sparingly), Methanol (Slightly) |
| Category | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | Tamoxifen Citrate is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. |
| References | Sutherland, R., et al.: Nature, 267, 434 |
