Sodium Salt Hydrate
Product Description
| Catalogue Number | L270005 |
| Chemical Name | LCZ696 Sodium Salt Hydrate |
| Synonyms | N-(1-Oxopentyl)-N-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-L-valine, compound with a-Ethyl (aR,gS)-g-[(3-carboxy-1-oxopropyl)amino]-a-methyl[1,1′-biphenyl]-4-pentanoate, Sodium Salt, Hydrate; Entresto; Sacubitril-valsartan; Sacubitril-valsartan Mixture |
| CAS Number | 1884447-69-1 |
| Alternate CAS # | 936623-90-4 |
| Molecular Formula | C₂₄H₂₇N₅Na₂O₃ • C ₂₄H₂₈NNaO₅ •xH₂O |
| Appearance | White to Off-White Solid |
| Melting Point | >188°C (dec.) |
| Molecular Weight | 479.48 + (433.47) + x(18.02) |
| Storage | 4°C |
| Solubility | DMSO (Slightly), Methanol (Sparingly) |
| Category | Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | LCZ696 is a novel dual-acting inhibitor of angiotensin II receptor and neprilysin, which can be used for blood pressure reduction. |
| References | Ruilope, L.M.; et al.: Lancet, 375, 1255 (2010) |
