Product Description

Catalogue Number S485000
Chemical Name Simvastatin
Synonyms 2,2-Dimethylbutanoic Acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl
CAS Number 79902-63-9
Molecular Formula C₂₅H₃₈O₅
Appearance White to Off-White Solid
Melting Point 112-125°C
Molecular Weight 418.57
Storage -20°C, Inert atmosphere
Solubility Acetonitrile (Sparingly), Chloroform (Slightly), Methanol (Slightly)
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications Simvastatin is a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hoffman, W.F., et al.: J. Med. Chem., 29, 849 (1986), Mol, M.J., et al.: Lancet, 2, 936 (1986),