Ivabradine Hydrochloride
Product Description
| Catalogue Number | I940500 |
| Chemical Name | Ivabradine Hydrochloride |
| Synonyms | 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride; Corlentor; Procoralan; S-16257; |
| CAS Number | 148849-67-6 |
| Alternate CAS # | Free Base: 155974-00-8 |
| Molecular Formula | C₂₇H₃₆N₂O₅ |
| Appearance | White to Light Yellow Solid |
| Melting Point | >190ºC (dec.) |
| Molecular Weight | 468.59 + 36.46 |
| Storage | -20°C |
| Solubility | DMSO (Sparingly, Sonicated), Methanol (Slightly), Water (Slightly) |
| Category | Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | Selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Antianginal. |
| Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package | |
| References | Thollon,C., et al.: Br. J. Pharmacol., 112, 37 (1994), Ragueneau, I., et al.: Clin. Pharmacol. Ther., 64, 192 (1998), Borer, J.S., et al.: Circulation, 107, 817 (2003), DiFrancesco, D., et al.: Drugs, 64, 1757 (2004), |
