Product Description

Catalogue Number I940500
Chemical Name Ivabradine Hydrochloride
Synonyms 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride; Corlentor; Procoralan; S-16257;
CAS Number 148849-67-6
Alternate CAS # Free Base: 155974-00-8
Molecular Formula C₂₇H₃₆N₂O₅
Appearance White to Light Yellow Solid
Melting Point >190ºC (dec.)
Molecular Weight 468.59 + 36.46
Storage -20°C
Solubility DMSO (Sparingly, Sonicated), Methanol (Slightly), Water (Slightly)
Category Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
Applications Selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Antianginal.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Thollon,C., et al.: Br. J. Pharmacol., 112, 37 (1994), Ragueneau, I., et al.: Clin. Pharmacol. Ther., 64, 192 (1998), Borer, J.S., et al.: Circulation, 107, 817 (2003), DiFrancesco, D., et al.: Drugs, 64, 1757 (2004),