Ibrutinib
Product Description
Catalogue Number | I124970 |
Chemical Name | Ibrutinib |
Synonyms | 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one; PCI 32765; PCI 32765-00; CRA 032765; (R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one |
CAS Number | 936563-96-1 |
Molecular Formula | C₂₅H₂₄N₆O₂ |
Appearance | White to Off-White Solid |
Melting Point | 153-158°C |
Molecular Weight | 440.5 |
Storage | 4°C |
Solubility | Chloroform (Sparingly), DMSO (Slightly), Methanol (Slightly, Sonicated) |
Category | Standards; Enzyme Activators and Inhibitors; |
Applications | Ibrutinib is a highly selective BrutonтАЩs tyrosine kinase (Btk) irreversible inhibitor. |
References | MacGlashan, D., et. al.: Int. Immunol., 11, 475 (2011) |