Product Description

Catalogue Number E565300
Chemical Name Epalrestat
Synonyms (5Z)-5-[(2E)-2-Methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-thiazolidineacetic Acid; Eabeth; Kinedak; ONO 2235; Sorbistat;
CAS Number 82159-09-9
Molecular Formula C₁₅H₁₃NO₃S₂
Appearance Red to Dark Orange Solid
Melting Point 214-218°C
Molecular Weight 319.4
Storage -20°C
Solubility DMSO (Slightly), Methanol (Sparingly)
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications An aldose reductase inhibitor. It is used in treatment of diabetic neuropathy.
References Terashima, H., et al.: J. Pharmacol. Exp. Ther., 229, 226 (1983), Kikkawa, R., et al.: Diabetologia, 24, 290 (1983), Kojima, K., et al.: Jpn. J. Ophthalmol., 29, 99 (1985),