Epalrestat
Product Description
Catalogue Number | E565300 |
Chemical Name | Epalrestat |
Synonyms | (5Z)-5-[(2E)-2-Methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-thiazolidineacetic Acid; Eabeth; Kinedak; ONO 2235; Sorbistat; |
CAS Number | 82159-09-9 |
Molecular Formula | C₁₅H₁₃NO₃S₂ |
Appearance | Red to Dark Orange Solid |
Melting Point | 214-218°C |
Molecular Weight | 319.4 |
Storage | -20°C |
Solubility | DMSO (Slightly), Methanol (Sparingly) |
Category | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
Applications | An aldose reductase inhibitor. It is used in treatment of diabetic neuropathy. |
References | Terashima, H., et al.: J. Pharmacol. Exp. Ther., 229, 226 (1983), Kikkawa, R., et al.: Diabetologia, 24, 290 (1983), Kojima, K., et al.: Jpn. J. Ophthalmol., 29, 99 (1985), |