Product Description

Catalogue Number E508000
Chemical Name Eltrombopag
Synonyms 3′-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2′-hydroxy-[1,1′-biphenyl]-3-carboxylic acid; SB 497115
CAS Number 496775-61-2
Molecular Formula C₂₅H₂₂N₄O₄
Appearance Orange to Dark Red Solid
Melting Point 236 – 238°C
Molecular Weight 442.47
Storage -20°C, Inert atmosphere
Solubility DMSO (Slightly), Methanol (Slightly, Heated)
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications An agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia.
References Bussel, J., et al.: New Eng. J. Med., 357, 2237 (2007),