Product Description

Catalogue Number C367365
Chemical Name 5-Chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine
Synonyms LDK378; Ceritinib; Zykadia
CAS Number 1032900-25-6
Molecular Formula C₂₈H₃₆ClN₅O₃S
Appearance White to Off-White Solid
Melting Point 173-175°C
Molecular Weight 558.14
Storage -20°C
Solubility Chloroform (Slightly), Methanol (Slightly)
Category Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications 5-Chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine, is a Anaplastic lymphoma kinase (ALK) inhibitor.
References Marsilje, T. H., et al.: J. Med. Chem., 56, 5675 (2013);