Product Description

Catalogue Number A803350
Chemical Name Azathioprine
Synonyms 6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-purine; BW-57-322; NSC-39084;
CAS Number 446-86-6
Molecular Formula C₉H₇N₇O₂S
Appearance Pale Yellow to Yellow Solid
Melting Point >225°C (dec.)
Molecular Weight 277.26
Storage -20°C
Solubility DMSO (Slightly), Methanol (Slightly, Heated)
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications An immunosuppressive antimetabolite. Also active as a disease modifying antirheumatic drug (DMARD). Azathioprine is a purine analog with immunosuppressive effects.
References Mitrou, P.S., et al.: Arzneim.-Forsch., 29, 483, 662 (1979), Ding, T.L., et al.: Drug. Metab. Dispos., 7, 373 (1979), Chan, G.L.C., et al.: Pharmacotherapy, 7, 165 (1987), Sandborn, W.J., et al.: : Scand. J. Gastroenterol., 33, Suppl. 225, 92 (1998,)