Azathioprine
Product Description
Catalogue Number | A803350 |
Chemical Name | Azathioprine |
Synonyms | 6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-purine; BW-57-322; NSC-39084; |
CAS Number | 446-86-6 |
Molecular Formula | C₉H₇N₇O₂S |
Appearance | Pale Yellow to Yellow Solid |
Melting Point | >225°C (dec.) |
Molecular Weight | 277.26 |
Storage | -20°C |
Solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
Category | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
Applications | An immunosuppressive antimetabolite. Also active as a disease modifying antirheumatic drug (DMARD). Azathioprine is a purine analog with immunosuppressive effects. |
References | Mitrou, P.S., et al.: Arzneim.-Forsch., 29, 483, 662 (1979), Ding, T.L., et al.: Drug. Metab. Dispos., 7, 373 (1979), Chan, G.L.C., et al.: Pharmacotherapy, 7, 165 (1987), Sandborn, W.J., et al.: : Scand. J. Gastroenterol., 33, Suppl. 225, 92 (1998,) |