Apixaban
Product Description
| Catalogue Number | A726700 |
| Chemical Name | Apixaban |
| Synonyms | 4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide; BMS 562247-01; 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic Acid Amide; |
| CAS Number | 503612-47-3 |
| Molecular Formula | C₂₅H₂₅N₅O₄ |
| Appearance | White to Off-White Solid |
| Melting Point | 235-238°C |
| Molecular Weight | 459.5 |
| Storage | 4°C |
| Solubility | DMSO (Slightly, Heated), Methanol (Slightly) |
| Category | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | A potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation. |
| References | Luettgen, J. M., et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T., et al.: J. Thromb. Thrombol., 31, 310 (2011); Barrett, Y. C., et al.: Thromb. Haemos., 105, 181 (2011); |
