Alogliptin Benzoate
Product Description
Catalogue Number | A575440 |
Chemical Name | Alogliptin Benzoate |
Synonyms | 2-[[6-[(3R)-3-Amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]benzonitrile Monobenzoate; Nesina; SYR 322; 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]benzonitrile Benzoate (1:1); (R)-2-((6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile Benzoate |
CAS Number | 850649-62-6 |
Molecular Formula | C₂₅H₂₇N₅O₄ |
Appearance | White to Pale Grey Solid |
Melting Point | 180-182°C |
Molecular Weight | 461.51 |
Storage | 4°C, Inert atmosphere |
Solubility | Aqueous Base (Slightly),Chloroform (Slightly), DMSO (Slightly), Methanol (Slight |
Category | Standards; Chiral Molecules; |
Applications | Alogliptin Benzoate is an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). Alogliptin Benzoate is used in the treatment of type 2 diabetes. |
References | Wang, Y., et. al.: Drugs Future, 33, 7 (2008); Lynn, F., et al.: Diabetes, 50, 1004 (2001); Trumper, A., et al.: J. Endocrinol., 174, 233 (2002); Vollmer, K., et al.: J. Clin. Endocrinol. Metab., 94, 1379 (2009) |