(S)-Omeprazole Sodium Salt
Product Description
| Catalogue Number | O635011 |
| Chemical Name | (S)-Omeprazole Sodium Salt |
| Synonyms | 6-Methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole Sodium Salt; (S)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl] |
| CAS Number | 161796-78-7 |
| Alternate CAS # | free acid: 119141-88-7 |
| Molecular Formula | C₁₇H₁₈N₃NaO₃S |
| Appearance | Pale Beige to Brown Solid |
| Melting Point | >151ºC (dec.) |
| Molecular Weight | 367.4 |
| Storage | 4°C, Hygroscopic |
| Solubility | DMSO (Slightly, Sonicated), Methanol (Slightly), Water (Slightly) |
| Stability | Hygroscopic |
| Category | Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | (S)-Omeprazole is the (S)-enantiomer of Omeprazole (O635000) a gastric proton-pump inhibitor. (S)-Omeprazole is more potent that its (R)-enantiomer and is used in the treatment of gastroesophageal reflux disease as well as gastrointestinal ulcers associated with Crohn’s disease. |
| References | Stedman, C.A.: Aliment. Pharmacol. Ther., 14, 963 (2000); Stenhoff, H., et al.: J. Chromatogr., 734, 191 (1999); Johnson, D.A., et al.: Expert Opin. Pharmacother., 4, 253 (2003); |
