Lesinurad
Product Description
| Catalogue Number | L329700 |
| Chemical Name | Lesinurad |
| Synonyms | [[5-bromo-4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid; |
| CAS Number | 878672-00-5 |
| Molecular Formula | C₁₇H₁₄BrN₃O₂S |
| Appearance | White to Off-White Solid |
| Melting Point | >171ºC (dec.) |
| Molecular Weight | 404.28 |
| Storage | -20°C, Inert atmosphere |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Category | Building Blocks; Enzyme Activators and Inhibitors; |
| Applications | Lesinurad is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout. |
| References | Burns, C., et al.: Lancet 377, 165 (2011); Miner, J. et al.: PCT Int. Appl. WOВ 2011159732В A1В 20111222 (2011);В Crittenden, D. B. et al.: Clinical InvestigationВ 1,В 1563-1575 (2011) |
