Baricitinib
Product Description
| Catalogue Number | B118690 |
| Chemical Name | Baricitinib |
| Synonyms | INCB 028050; LY 3009104; 1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile; 2-(3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetonitrile |
| CAS Number | 1187594-09-7 |
| Molecular Formula | C₁₆H₁₇N₇O₂S |
| Appearance | White to Off-White Solid |
| Melting Point | 212-215°C |
| Molecular Weight | 371.42 |
| Storage | 4°C |
| Solubility | Chloroform (Slightly, Heated), DMSO (Slightly) |
| Category | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | Baricitinib is a JAK1 and JAK2 inhibitor and have been used as a promising treatment for rheumatoid arthritis. |
| References | Greenwald, L.J., et al.: Int. J. Clin. Rheumatol., 6, 401 (2011); Fridman, J.S., et al.: J. Immunol., 184, 5298 (2010); |
