Upadacitinib
Product Description
| Catalogue Number | U800075 |
| Chemical Name | Upadacitinib |
| Synonyms | ABT-494; rel-(-)-(3S,4R)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide; (3S,4R)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)-1-pyrrolidinecarboxamide |
| CAS Number | 1310726-60-3 |
| Molecular Formula | C₁₇H₁₉F₃N₆O |
| Molecular Weight | 380.37 |
| Category | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | Upadacitinib also known as ABT-494, is a potent and selective Janus kinase (JAK) 1 inhibitor being developed for the treatment of several autoimmune disorders, Janus kinase inhibitors for rheumatoid arthritis. |
| References | Mohamed, M. F., et al.: Clin. Pharmacokinet., 55, 1547 (2016); Semerano, L., et al.: Expert Opin. on Investig. Drugs, 25, 1355 (2016) |
