Anlotinib Dihydrochloride
Product Description
| Catalogue Number | A678535 |
| Chemical Name | Anlotinib Dihydrochloride |
| Synonyms | 1-[[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-quinolinyl]oxy]methyl]cyclopropanamine Hydrochloride (1:2); AL3818 Dihydrochloride |
| CAS Number | 1360460-82-7 |
| Alternate CAS # | HCl: 1058156-90-3 |
| Molecular Formula | C₂₃H₂₂FN₃O₃ • 2HCl |
| Appearance | Off-White to Pale Brown Solid |
| Melting Point | >252°C (dec.) |
| Molecular Weight | 407.44 + 2(36.46) |
| Storage | 4°C |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Category | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | Anlotinib Dihydrochloride, is a novel inhibitor of tyrosine kinase that is designed to primarily inhibit VEGFR2/3, FGFR1-4, PDGFRa/b, c-Kit, and Ret. |
| References | Sun, Y. et al.: J Hematol Oncol. 2016 Oct 4;9(1):105; Taurin, S. et al.: Int J Gynecol Cancer. 2018 Jan;28(1):152-160; |
