Ceritinib
Product Description
Catalogue Number | C367365 |
Chemical Name | 5-Chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine |
Synonyms | LDK378; Ceritinib; Zykadia |
CAS Number | 1032900-25-6 |
Molecular Formula | C₂₈H₃₆ClN₅O₃S |
Appearance | White to Off-White Solid |
Melting Point | 173-175°C |
Molecular Weight | 558.14 |
Storage | -20°C |
Solubility | Chloroform (Slightly), Methanol (Slightly) |
Category | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
Applications | 5-Chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine, is a Anaplastic lymphoma kinase (ALK) inhibitor. |
References | Marsilje, T. H., et al.: J. Med. Chem., 56, 5675 (2013); |